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Mercoledì, 30 Luglio 2014 20:49

8-oxo-guanosine (8oHdG) and neurodegeneration: clinical case

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La guanosina deossidata è un test sulle urine che supporta la tesi di rilevante stress ossidativo nell'autismo ed in molte patologie degenerative

Mia figlia è da tre anni che sta facendo trattamenti biomedici incrociati con una continua progressione sia in termini autoimmunitari che di metalli pesanti che di autoimmunità con milgioramento della performance generale ed inizio di linguaggio verbale con maggiore livello della comprensione.

Nel 2012 ad analisi biomolecolari è risultato fuori range per questo biomarkers di stress ossidativo a livello del DNA cellulare

 

Dopo due anni ho rifatto un altro esame biomolecolare dove era contemplato anche questo biomarkers ed ecco il risultato

Siamo passati da 24,3 = grave stress ossidativo a 4,1 che è nei valori normali

Sarà un caso che migliorando ed in questo caso risolvendo lo stress ossidativo mia figlia ha fatto moltissimi progressi?

a voi i commenti del caso

 

8-oxo-guanosine (8oHdG) and neurodegeneration
8oHdG is an RNA oxidative damage marker that can be
used to assess oxidative stress that is found in the brain in
neurodegenerative disease [62]. Urinary 8OHdG has been
used successfully to measure brain damage and degeneration,
showing a significant correlation (r = 0.87, p < 0.01)
with serum S100beta values, which are already used to
measure brain damage [63]. Sajdel-Sulkowska et al [58]
conducted a study where they examined oxidative damage
in the cerebellum of those individuals diagnosed with an
ASD by measuring 8OHdG. The authors found that cerebellar
8OHdG showed an upward trend toward higher
levels with an increase of 63.4% observed in those individuals
diagnosed with an ASD in comparison to controls.

Letto 3643 volte Ultima modifica il Mercoledì, 30 Luglio 2014 21:09
Salvatore Morelli

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