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Sabato, 10 Maggio 2014 23:32

Sistema degli Endocannabinoidi: antinfiammatori ed immunomodulatori

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Sistema degli Endocannabinoidi: antinfiammatori ed immunomodulatori

Nuovi studi sul sistema degli endocannabinoidi

Secondo questa recentissima ricerca, peraltro fatta in Italia, 

http://www.medicinalgenomics.com/wp-content/uploads/2014/01/Siniscalco-et-al-CB2-upregulation-in-autism-2013.pdf o vedi gli allegati,

Gli endocannabinoidi attiverebbero i recettori CB2 che sarebbero immunosoppressivi.

Inoltre  l'attivazione dei recetori CB2  permetterebbe la modulazione ed delle citochine infiammatorie.

 

Quindi l'attivazione dei recettori CB2 permetterebbe una funzione sia antinfiammatoria che immunomodulatrice

"Emerging studies highlight that endocannabinoid signalling
through CB2 receptors could activate a protective system.
CB2 receptor activation is known to trigger immune suppression
(Hegde et al. 2010). After inflammation or tissue
injury, there is a rapid increase in local endocannabinoid
levels, which appears to mediate immune responses through
down-regulation of cytokine expressions (Jean-Gilles et al.
2010; Pacher and Mechoulam 2011). The immunomodulatory
effects of endocannabinoids are mainly mediated by
the CB2 receptor expressed on immune cells"

Letto 2548 volte Ultima modifica il Domenica, 11 Maggio 2014 00:21
Pubblicato in AUTOIMMUNITA' AUTISTICA SNC
Download allegati:
Salvatore Morelli

web designer, web master, multimedia editor, graphic designer, digital video master, streaming producer, progettista ed amministratore piattaforme FAD, elearning content editor, audio content editor, Digital Video Streaming-Editor ed infine logopedista

Ultimi da Salvatore Morelli

Altro in questa categoria: « Cerebral folate receptor autoantibodies in autism spectrum disorder Mycobacterium paratuberculosis: è forse una causa dell'autismo? »
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